细胞外基质蛋白对先天性牙发育畸形的影响及机制
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中图分类号:

Q254,R78

基金项目:

中国医学科学院医学与健康科技创新工程项目 (2019-12M-5-031)


The effects and mechanisms of extracellular matrix proteins on congenital tooth malformation
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    摘要:

    先天性牙发育畸形是指在胚胎发育期间或出生后,牙齿形态或结构异常的一类牙齿疾病。这类畸形可能会对牙齿的生长、咀嚼功能和美观等方面产生影响,严重的还可能影响患者的口腔健康和生活质量。先天性牙发育畸形病因及致病机制复杂,影响牙齿发育的多种因素都可能导致牙发育畸形。细胞外基质蛋白是一类存在于牙齿的细胞外基质中的蛋白质,对牙齿的生长、发育和维持牙齿的健康具有重要作用。本文对细胞外基质蛋白在先天性牙发育畸形中的作用及影响机制进行阐述,为深入理解先天性牙发育畸形的病因、致病机制及防治提供依据。

    Abstract:

    Congenital tooth developmental anomalies refer to a type of tooth disease where the shape or structure of the teeth is abnormal during embryonic development or after birth. Such anomalies may affect the growth, chewing function, and aesthetics of the teeth, and in severe cases, may also affect the oral health and quality of life of patients. The etiology and pathogenesis of congenital tooth developmental anomalies are complex, and various factors that affect tooth development may lead to these anomalies. Extracellular matrix proteins are a type of protein present in the extracellular matrix of teeth that play an important role in tooth growth, development, and maintenance of tooth health. This article elaborates the role and impact mechanism of extracellular matrix proteins in congenital tooth developmental anomalies, providing a basis for a better understanding of the etiology, pathogenesis, prevention, and treatment of congenital tooth developmental anomalies.

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历史
  • 收稿日期:2023-07-25
  • 最后修改日期:2023-08-21
  • 在线发布日期: 2023-09-27
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