With an escalating global epidemic of obesity, the prevalence of obesity among reproductive women continues to rise. It has been widely reported that maternal obesity has profound effects on female reproduction. Of them, oocyte quality has been a major concern. In recent years, emerging evidence on maternal obesity has shown that meiosis damage, mitochondrial and endoplasmic reticulum dysfunction, and epigenetic modification changes occur in oocytes, and mechanisms are also being reported. Here we review the recent researches on the effects of maternal obesity on oocyte and embryo development, and propose the potential intervention targets and pathways to improve egg quality and reproductive outcome.