国家自然科学基金 （创新研究群体项目：82021002；重点项目：81830063；青年项目：81801363）；上海市科委科研计划项目（19MC1910500；18411950100）；上海市卫生和计划生育委员会科研课题资助项目 （20184Y0111；201640176）；上海市“医苑新星”青年医学人才培养资助计划。
Limb paralysis is the main cause of human disability. Hemiplegia caused by stroke alone has affected more than 20 million patients in China, and there is currently no cure for this disease. We created the original contralateral C7 to C7 cross nerve transfer surgery that swapped the link of the brachial nerve of the paralyzed side to the ipsilateral healthy brain. Not only did hemiplegic limb function recover significantly, it also broke the traditional neuroscience theory. However, for patients with limb paralysis or severe limb disability after spinal cord injury, the practicality of traditional medical methods is still facing the doubt of effectiveness. In recent years, interdisciplinary cooperation derived from emerging technologies such as brain-computer interfaces based on the development of traditional EEG technology have gradually risen. They have the potential to solve the problems left over from traditional medicine and have taken a great upsurge at home and abroad. As a national strategic demand, we should seize this opportunity to increase our efforts to support cross-field and multi-disciplinary integration to jointly develop new solutions for limb function reconstruction, and achieve another breakthrough in the integration of emerging technologies and Chinese original technologies.