Chronic pancreatitis (CP) is a progressive inflammatory disease of the pancreas in individuals with genetic, environmental, and/or other risk factors. In recent years, CP has aroused extensive attentions of the researchers worldwide and several high qualified clinical guidelines and studies were published. CP is characterized by increasing incidence, complex etiology and pathogenesis, variable clinical courses, difficult early diagnosis, and low life quality of patients. A plenty of issues in basic and clinical researches of CP need to be explained and solved. This review outlined the important basic and clinical researches of CP currently, to provide some references for this field.